It means "can't stand it". 頂 ding in Cantonese means "to stand against" - 究竟係「冇得頂」定「定唔順」定「頂唔泡」呢?
http://www.rm501.net/?p=480
http://centralsaintstudent.blogspot.com/2006/08/blog-post_07.html
By volume, cartridge ink has become more expensive than Chanel No 5 Eau De Parfum.
